LIST OF DIRECTORS AND THEIR ROLES AND FUNCTIONS Discover——

APPOINTMENT OF INDEPENDENT NON-EXECUTIVE DIRECTOR; CHANGE IN COMPOSITION OF THE BOARD COMMITTEES ; AND COMPLIANCE WITH RULE 3.10(2), 3.21, 3.25 AND 3.27A OF THE LISTING RULES Discover——

Monthly Return of Equity Issuer on Movements in Securities for the Month ended 30 November 2025 Discover——

Monthly Return of Equity Issuer on Movements in Securities for the Month ended 31 October 2025 Discover——

POLL RESULTS OF 2025 SECOND EXTRAORDINARY GENERAL MEETING HELD ON OCTOBER 30, 2025 Discover——

VOLUNTARY ANNOUNCEMENT – CLINICAL POSITIVE DATA FOR CDK INHIBITORS ANNOUNCED AT ESMO CONGRESS 2025 Discover——

FORM OF PROXY FOR THE SECOND EXTRAORDINARY GENERAL MEETING OF 2025 TO BE HELD ON THURSDAY, OCTOBER 30, 2025 AND ANY ADJOURNMENT THEREOF Discover——

PROPOSED AMENDMENTS TO THE ARTICLES OF ASSOCIATION; PROPOSED ABOLISHMENT OF THE BOARD OF SUPERVISORS; PROPOSED AMENDMENTS TO THE RULES OF PROCEDURE FOR THE BOARD OF DIRECTORS; Discover——

NOTICE OF THE SECOND EXTRAORDINARY GENERAL MEETING OF 2025 Discover——

CIRCULAR OF THE SECOND EXTRAORDINARY GENERAL MEETING OF 2025 Discover——

BOOK CLOSURE PERIOD FOR EXTRAORDINARY GENERAL MEETING Discover——

Monthly Return of Equity Issuer on Movements in Securities for the Month ended 30 September 2025 Discover——

Notification Letter to Non-registered H Shareholders and Reply Form – Reminder letter regarding the Arrangement of Electronic Dissemination of Corporate Communications Discover——

Notification Letter to Registered H Shareholders and Reply Form – Reminder letter regarding the Arrangement of Electronic Dissemination of Corporate Communications Discover——

LIST OF DIRECTORS AND THEIR ROLES AND FUNCTIONS Discover——

RESIGNATION OF INDEPENDENT NON-EXECUTIVE DIRECTOR AND TEMPORARY NON-COMPLIANCE WITH RELEVANT LISTING RULES Discover——

Monthly Return of Equity Issuer on Movements in Securities for the Month ended 31 August 2025 Discover——

Monthly Return of Equity Issuer on Movements in Securities for the Month ended 31 July 2025 Discover——

INTERIM RESULTS ANNOUNCEMENT FOR THE SIX MONTHS ENDED JUNE 30, 2025; RESIGNATION OF NON-EXECUTIVE DIRECTOR;AND PROPOSED AMENDMENTS TO THE ARTICLES OF ASSOCIATION Discover——

PLACING OF NEW H SHARES UNDER GENERAL MANDATE Discover——

FORM OF PROXY FOR THE ANNUAL GENERAL MEETING OF 2024 TO BE HELD ON THURSDAY, JUNE26, 2025 AND ANY ADJOURNMENT THEREOF Discover——

DISCLOSEABLE TRANSACTIONS – SUBSCRIPTION OF WEALTH MANAGEMENT PRODUCTS; INVESTMENT AND REDEMPTION OF FUND INTEREST; AND UPDATE IN USE OF IDLE FUNDS FROM THE GLOBAL OFFERING Discover——

INSIDE INFORMATION – POTENTIAL MASTER DISTRIBUTION ARRANGEMENT WITH SICHUAN HUIYU PHARMACEUTICAL CO., LTD. Discover——

VOLUNTARY ANNOUNCEMENT – PHASE I CLINICAL TRIAL RESULTS OF TY-302, TY-2699a AND TY-0540 ACCEPTED FOR POSTER PRESENTATION AT THE 2025 EUROPEAN SOCIETY FOR MEDICAL ONCOLOGY (ESMO) CONGRESS Discover——

LIST OF DIRECTORS AND THEIR ROLES AND FUNCTIONS Discover——

Monthly Return of Equity Issuer on Movements in Securities for the Month ended 31 May 2025 Discover——

RESIGNATION OF SENIOR MANAGEMENT AND JOINT COMPANY SECRETARY; AND RE-DESIGNATION OF AN EXECUTIVE DIRECTOR TO A NON-EXECUTIVE DIRECTOR Discover——

ANNUAL RESULTS ANNOUNCEMENT FOR THE YEAR ENDED DECEMBER 31, 2024; RESIGNATION OF NON-EXECUTIVE DIRECTOR; AND PROPOSED AMENDMENTS TO THE ARTICLES OF ASSOCIATION Discover——

DATE OF BOARD MEETING Discover——

Next Day Disclosure Return Discover——

MONTHLY RETURNS Monthly Return of Equity Issuer on Movements in Securities for the Month ended 31 December 2024 Discover——

INSIDE INFORMATION – ISSUANCE OF FILING NOTICE BY THE CSRC FOR THE H SHARE FULL CIRCULATION APPLICATION OF THE COMPANY Discover——

MONTHLY RETURNS-Monthly Return of Equity Issuer on Movements in Securities for the Month ended 31 October 2024 Discover——

LIST OF DIRECTORS AND THEIR ROLES AND FUNCTIONS Discover——

ANNOUNCEMENT IN RELATION TO DEALINGS IN SECURITIES OF A DIRECTOR DURING THE BLACK-OUT PERIOD Discover——

DATE OF BOARD MEETING Discover——

VOLUNTARY ANNOUNCEMENT – EGFR-TARGETED INNOVATIVE DRUG ASANDEUTERTINIB DEMONSTRATES BREAKTHROUGH EFFICACY IN NSCLC PATIENTS WITH BRAIN METASTASES Discover——

COMPLETION OF PLACING OF NEW H SHARES UNDER THE GENERAL MANDATE Discover——

Next Day Disclosure Returns Discover——

Monthly Return of Equity Issuer on Movements in Securities for the Month ended 30 June 2025 Discover——

LIST OF DIRECTORS AND THEIR ROLES AND FUNCTIONS Discover——

POLL RESULTS OF THE 2024 ANNUAL GENERAL MEETING HELD ON JUNE 26, 2025; AND APPOINTMENT OF NON-EXECUTIVE DIRECTOR Discover——

INSIDE INFORMATION APPLICATION FOR THE H SHARE FULL CIRCULATION BY THE COMPANY Discover——

CIRCULAR OF 2024 AGM Discover——

NOTICE OF THE 2024 ANNUAL GENERAL MEETING Discover——

VOLUNTARY ANNOUNCEMENT INCLUSION AS A CONSTITUENT OF HANG SENG BIOTECH INDEX Discover——

PROPOSED APPOINTMENT OF NON-EXECUTIVE DIRECTOR Discover——

Monthly Return of Equity Issuer on Movements in Securities for the Month ended 30 April 2025 Discover——

CONNECTED TRANSACTION PARTICIPATION IN ESTABLISHMENT OF FUND Discover——

Monthly Return of Equity Issuer on Movements in Securities for the Month ended 31 March 2025 Discover——

LIST OF DIRECTORS AND THEIR ROLES AND FUNCTIONS Discover——

TERMS OF REFERENCE OF THE NOMINATION COMMITTEE OF THE BOARD OF DIRECTORS Discover——

INVESTIGATOR DATA SHOW PIVOTAL PHASE II CLINICAL TRIAL OF TY-9591 VERSUS OSIMERTINIB AS A FIRST-LINE TREATMENT FOR BRAIN METASTASES FROM LUNG CANCER WITH EGFR MUTATIONS MET EXPECTATIONS WITH STATISTICAL AND CLINICAL SIGNIFICANCE Discover——

MONTHLY RETURNS Monthly Return of Equity Issuer on Movements in Securities for the Month ended 28 February 2025 Discover——

INSIDE INFORMATION COMPLETION OF THE H SHARE FULL CIRCULATION Discover——

INSIDE INFORMATION GRANT OF LISTING APPROVAL BY THE STOCK EXCHANGE FOR IMPLEMENTATION OF THE H SHARE FULL CIRCULATION Discover——

MONTHLY RETURNS-Monthly Return of Equity Issuer on Movements in Securities for the Month ended 31 January 2025 Discover——

Results of EGM/SGM- POLL RESULTS OF 2025 FIRST EXTRAORDINARY GENERAL MEETING HELD ON JANUARY 3, 2025 Discover——

Amendment of Constitutional Documents / Other- CIRCULAR OF THE FIRST EXTRAORDINARY GENERAL MEETING OF 2025 Discover——

Notice of EGM/SGM / Closure of Books or Change of Book Closure Period- NOTICE OF THE FIRST EXTRAORDINARY GENERAL MEETING OF 2025 Discover——

Proxy Forms- FORM OF PROXY FOR THE FIRST EXTRAORDINARY GENERAL MEETING OF 2025 TO BE HELD ON FRIDAY, JANUARY 3, 2025 AND ANY ADJOURNMENT THEREOF Discover——

Closure of Books or Change of Book Closure Period- BOOK CLOSURE PERIOD FOR EXTRAORDINARY GENERAL MEETING Discover——

Continuing Connected Transaction- CONTINUING CONNECTED TRANSACTION ADVANCEMENT TO CONNECTED PERSON IN RELATION TO INDIVIDUAL INCOME TAX ARISING FROM THE AWARDS UNDER THE EMPLOYEE INCENTIVE SCHEME Discover——

Amendment of Constitutional Documents-PROPOSED AMENDMENTS TO THE ARTICLES OF ASSOCIATION Discover——

INSIDE INFORMATION APPLICATION FOR THE H SHARE FULL CIRCULATION BY THE COMPANY Discover——

MONTHLY RETURNS-Monthly Return of Equity Issuer on Movements in Securities for the Month ended 30 November 2024 Discover——

MONTHLY RETURNS-Monthly Return of Equity Issuer on Movements in Securities for the Month ended 30 September 2024 Discover——

Circulars – Notification Letter to Non-registered H Shareholders and Reply Form – Arrangement of Electronic Dissemination of Corporate Communications Discover——

Circulars – Notification Letter to Registered H Shareholders and Reply Form – Arrangement of Electronic Dissemination of Corporate Communications Discover——

MONTHLY RETURNS-Monthly Return of Equity Issuer on Movements in Securities for the Month ended 31 August 2024 Discover——

CLARIFICATION ANNOUNCEMENT Discover——

Date of Board Meeting Discover——